One-Shot gene editing could end debilitating pain crises
NCT ID NCT05456880
Summary
This study is testing a new, one-time treatment for severe sickle cell disease. Doctors take a patient's own blood stem cells, edit their genes in a lab, and then return them to the patient. The goal is to see if this single treatment can safely and significantly reduce the number of painful and dangerous blood vessel blockages (crises) that patients experience.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SICKLE CELL DISEASE are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Boston Children's Hospital
Boston, Massachusetts, 02215, United States
-
Children's Healthcare of Atlanta - Aflac Cancer and Blood Disorders Center - Egleston Hospital
Atlanta, Georgia, 30329, United States
-
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
-
Columbia University Irving Medical Center
New York, New York, 10032, United States
-
Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
-
Henry Ford Cancer Center
Detroit, Michigan, 48202, United States
-
Mayo Clinic Florida
Jacksonville, Florida, 32224, United States
-
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
-
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
-
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
-
Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
-
St Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
-
The Children's Hospital at TriStar Centennial
Nashville, Tennessee, 37203, United States
-
The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
-
University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
-
University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
-
University of Miami
Miami, Florida, 33136-1005, United States
-
University of Minnesota
Minneapolis, Minnesota, 55455, United States
-
Washington University School of Medicine in St. Louis
St Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.