Experimental cancer drug GEN1047 tested in humans – study halted early
NCT ID NCT05180474
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This study tested a new drug called GEN1047 in people with advanced solid tumors (breast, endometrial, ovarian, or lung cancer) who had no other treatment options. The goal was to check safety, side effects, and how the body processes the drug. The study was terminated early, but the data may still help understand the drug's potential.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Antwerp University Hospital
Edegem, 2650, Belgium
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Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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CHU Poitiers - Hôpital la Milétrie
Poitiers, France
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CHU de Besancon
Besançon, 25030, France
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Centre Léon Bérard
Lyon, 69008, France
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Centro Oncologico Clara Campal
Madrid, 28050, Spain
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Clinica Universidad de Navarra
Pamplona, 31008, Spain
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Erasmus Medisch Centrum
Rotterdam, 3015CE, Netherlands
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Fondazione IRCCS San Gerardo dei Tintori
Monza, 20900, Italy
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Hospital Clinic de Barcelona
Barcelona, Spain
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Hospital Clinico Universitario de Valencia
Valencia, Spain
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Hospital Ruber Internacional
Madrid, 28034, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 8035, Spain
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Hospital Universitary Fundacion Jimenez Diaz
Madrid, 2815, Spain
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Hôpital Cochin
Paris, France
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IEO Istituto Europeo di Oncologia
Milan, 435, Italy
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Institut Bergonié
Bordeaux, France
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Institut Claudius Regaud
Toulouse, France
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Institut Curie
Paris, 75248, France
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Institut Gustave Roussy
Villejuif, 75005, France
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Institut du Cancer de Montpellier
Montpellier, 34298, France
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MD Anderson Cancer Center
Madrid, 28033, Spain
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Med-Polonia Sp. z o.o
Poznan, Poland
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NEXT Oncology Madrid
Madrid, Spain
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Radboudumc
Nijmegen, 6525GA, Netherlands
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Rigshospitalet (Copenhagen University Hospital)
Copenhagen, 2100, Denmark
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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St Bartholomews Hospital
London, EC1A7BE, United Kingdom
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The Christie Hospital
Manchester, M20 4BX, United Kingdom
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UCLA Department of Medicine Hematology Oncology
Los Angeles, California, 90024, United States
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Universitair Ziekenhuis Leuven
Leuven, 3000, Belgium
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University College London Hospital
London, NW1 2BU, United Kingdom
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University Medical Center Groningen
Groningen, 9713GZ, Netherlands
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Yale University - Yale Cancer Center
New Haven, Connecticut, 06520-8028, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.