New cancer drug enters human testing for Hard-to-Treat tumors
NCT ID NCT05180474
Summary
This is the first human trial testing a new cancer drug called GEN1047 in people with advanced solid tumors, including breast, ovarian, endometrial, and a type of lung cancer. The main goals are to find a safe dose and see if the drug helps shrink tumors. All 179 participants will receive the active drug, with no one getting a placebo.
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Contacts and locations
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Locations
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Antwerp University Hospital
Edegem, 2650, Belgium
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Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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CHU Poitiers - Hôpital la Milétrie
Poitiers, France
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CHU de Besancon
Besançon, 25030, France
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Centre Léon Bérard
Lyon, 69008, France
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Centro Oncologico Clara Campal
Madrid, 28050, Spain
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Clinica Universidad de Navarra
Pamplona, 31008, Spain
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Erasmus Medisch Centrum
Rotterdam, 3015CE, Netherlands
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Fondazione IRCCS San Gerardo dei Tintori
Monza, 20900, Italy
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Hospital Clinic de Barcelona
Barcelona, Spain
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Hospital Clinico Universitario de Valencia
Valencia, Spain
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Hospital Ruber Internacional
Madrid, 28034, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 8035, Spain
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Hospital Universitary Fundacion Jimenez Diaz
Madrid, 2815, Spain
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Hôpital Cochin
Paris, France
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IEO Istituto Europeo di Oncologia
Milan, 435, Italy
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Institut Bergonié
Bordeaux, France
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Institut Claudius Regaud
Toulouse, France
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Institut Curie
Paris, 75248, France
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Institut Gustave Roussy
Villejuif, 75005, France
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Institut du Cancer de Montpellier
Montpellier, 34298, France
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MD Anderson Cancer Center
Madrid, 28033, Spain
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Med-Polonia Sp. z o.o
Poznan, Poland
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NEXT Oncology Madrid
Madrid, Spain
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Radboudumc
Nijmegen, 6525GA, Netherlands
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Rigshospitalet (Copenhagen University Hospital)
Copenhagen, 2100, Denmark
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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St Bartholomews Hospital
London, EC1A7BE, United Kingdom
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The Christie Hospital
Manchester, M20 4BX, United Kingdom
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UCLA Department of Medicine Hematology Oncology
Los Angeles, California, 90024, United States
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Universitair Ziekenhuis Leuven
Leuven, 3000, Belgium
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University College London Hospital
London, NW1 2BU, United Kingdom
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University Medical Center Groningen
Groningen, 9713GZ, Netherlands
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Yale University - Yale Cancer Center
New Haven, Connecticut, 06520-8028, United States
Conditions
Explore the condition pages connected to this study.