New combo therapy targets rare sarcomas in early trial
NCT ID NCT06308419
First seen Nov 16, 2025 · Last updated Apr 25, 2026 · Updated 14 times
Summary
This early-phase trial tests a combination of two drugs, gemcitabine and nab-sirolimus, in people with advanced leiomyosarcoma or soft-tissue sarcoma that has a specific genetic change (TSC1 or TSC2 mutation). The main goal is to find a safe dose and see how well the body tolerates the treatment. About 18 participants will take part in this study at M.D. Anderson Cancer Center.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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