Engineered immune cells take on tough childhood cancers in new trial
NCT ID NCT04539366
First seen Nov 03, 2025 · Last updated May 01, 2026 · Updated 28 times
Summary
This early-stage trial tests a personalized cell therapy called GD2CART for children and young adults with osteosarcoma or neuroblastoma that has returned or not responded to standard treatments. The therapy uses the patient's own immune cells, modified to recognize and attack cancer cells carrying the GD2 protein. The main goals are to see if the cells can be made successfully, find the safest dose, and check for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Lucile Packard Children's Hospital Stanford University
Palo Alto, California, 94304, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
Conditions
Explore the condition pages connected to this study.