One-Shot gene therapy trial offers hope for infants with devastating muscle disease

NCT ID NCT07070999

Summary

This study is testing a single dose of an experimental gene therapy called GB221 for babies with spinal muscular atrophy type 1 (SMA1). The goal is to see if delivering a working copy of the missing SMN1 gene directly to the nervous system is safe and can help improve muscle function. It includes babies from 2 weeks to under 12 months old who already have symptoms, as well as younger babies who are at risk but don't yet show symptoms.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital de Clínicas de Porto Alegre

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

Conditions

Explore the condition pages connected to this study.