One-Shot gene therapy trial offers hope for gaucher disease patients

NCT ID NCT05487599

Summary

This early-stage study is testing a single intravenous dose of an experimental gene therapy called LY3884961 in adults with Gaucher disease. The main goal is to see if the treatment is safe and tolerable, while also checking if it can improve key disease measures like spleen size and blood counts. Up to 15 participants will be followed for about 5 years to monitor long-term effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann and Robert H Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27710-3017, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Quironsalud Zaragoza, Paseo Mariano Renovales Sn

    RECRUITING

    Zaragoza, 50006, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital de Clinicas de Porto Alegre (HCPA)

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lysosomal & Rare Disorders Research and Treatment Center

    RECRUITING

    Fairfax, Virginia, 22030-6066, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Free Hospital NHS Trust

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SphinCS Clinical Science for LSD

    RECRUITING

    Höchheim, 65239, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Westmead Hospital-Cnr Hawkesbury and Darcy Rds

    COMPLETED

    Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.