Stomach cancer surgery showdown: which reconstruction method improves life quality?

NCT ID NCT06768164

Recruiting now Symptom relief Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common surgical techniques used to reconnect the digestive tract after partial stomach removal for gastric cancer: Billroth II (one connection) and Roux-en-Y (two connections). The goal is to see which method leads to better quality of life one year after surgery, focusing on eating, reflux, and pain. About 250 adults with stomach cancer will be randomly assigned to one of the two procedures and followed for a year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical procedure (Billroth II or Roux-en-Y reconstruction)
What this could lead to: If successful, this study could show which surgical method after partial stomach removal gives patients a better quality of life with fewer eating problems, reflux, and pain.
What could go wrong: This is a Phase 3 trial, but it only compares two existing surgical techniques, not a new drug. The results may not apply to all patients, and individual outcomes can vary.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRIC (CARDIA, BODY) CANCER

Contacts and locations

Locations

Hôpital Saint-Antoine
RECRUITING

Paris, 75012, France

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