New shot may stop dangerous swelling in kids with rare disease

NCT ID NCT05819775

First seen Jan 29, 2026 · Last updated May 14, 2026 · Updated 18 times

Summary

This study tested a monthly injection called garadacimab to prevent sudden swelling attacks in children aged 2 to 11 with hereditary angioedema (HAE). The goal was to see if the drug is safe and reduces how often attacks happen. 22 children took part, and researchers tracked side effects and attack rates over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AARA Research Center

    Dallas, Texas, 75231, United States

  • Barzilai University Medical Center

    Ashkelon, 7830604, Israel

  • Bernstein Clinical Research

    Cincinnati, Ohio, 45236, United States

  • Campbelltown Hospital, Western Sydney University

    Campbelltown, NSW 2560, Australia

  • Charité - Universitätsmedizin Berlin

    Berlin, 12203, Germany

  • Donald S. Levy M.D.

    Orange, California, 92868, United States

  • HZRM Hämophilie Zentrum Rhein Main GmbH

    Frankfurt am Main, Hesse, 60596, Germany

  • Medical Research of Arizona

    Scottsdale, Arizona, 85251, United States

  • Ottawa Allergy Research Corp

    Ottawa, K1H1E4, Canada

  • PennState Health Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Raffi Tachdjian MD, Inc.

    Santa Monica, California, 90404, United States

  • Research Solutions of Arizona

    Litchfield Park, Arizona, 85340, United States

  • Universitätsklinikum Frankfurt

    Frankfurt am Main, 60590, Germany

Conditions

Explore the condition pages connected to this study.