New shot could stop painful swelling attacks in kids
NCT ID NCT05819775
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called Garadacimab in 22 children aged 2 to 11 with hereditary angioedema, a condition that causes sudden, painful swelling. The drug is given as a shot under the skin to prevent attacks. The study looked at safety and how well it works. It has already been completed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Garadacimab (a lab-made antibody given as a shot under the skin)
What this could lead to
If it works, this could give children with hereditary angioedema a new option to prevent painful swelling attacks.
What could go wrong
This is a small, completed study with only 22 children, so results may not apply to everyone. Side effects or lack of effectiveness are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AARA Research Center
Dallas, Texas, 75231, United States
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Barzilai University Medical Center
Ashkelon, 7830604, Israel
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Bernstein Clinical Research
Cincinnati, Ohio, 45236, United States
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Campbelltown Hospital, Western Sydney University
Campbelltown, NSW 2560, Australia
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Charité - Universitätsmedizin Berlin
Berlin, 12203, Germany
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Donald S. Levy M.D.
Orange, California, 92868, United States
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HZRM Hämophilie Zentrum Rhein Main GmbH
Frankfurt am Main, Hesse, 60596, Germany
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Medical Research of Arizona
Scottsdale, Arizona, 85251, United States
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Ottawa Allergy Research Corp
Ottawa, K1H1E4, Canada
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PennState Health Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
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Raffi Tachdjian MD, Inc.
Santa Monica, California, 90404, United States
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Research Solutions of Arizona
Litchfield Park, Arizona, 85340, United States
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Universitätsklinikum Frankfurt
Frankfurt am Main, 60590, Germany