New eye drops aim to halt blinding disease in seniors

NCT ID NCT06659549

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study tests whether GAL-101 eye drops can slow the growth of geographic atrophy, a form of advanced age-related macular degeneration that causes blind spots. About 110 adults aged 55 and older with early-stage atrophy will use the drops or a placebo daily for up to two years. The goal is to see if the treatment can keep the damage from reaching the center of vision.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
GAL-101 eye drops
What this could lead to
If successful, this could slow vision loss from geographic atrophy and help preserve central vision in elderly patients.
What could go wrong
This is an early Phase 2 trial with only 110 participants. The drug may not slow atrophy growth, and daily eye drops may be inconvenient or cause irritation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Akhali Mzera Limited

    RECRUITING

    Tbilisi, 0162, Georgia

  • Bay Area Retina Associates

    RECRUITING

    Walnut Creek, California, 94598, United States

  • Caucasus Medical Centre LLC

    RECRUITING

    Tbilisi, 0186, Georgia

  • Centre Monticelli Paradis d'Ophtalmologie

    RECRUITING

    Marseille, 13008, France

  • Centre Ophtalmologique Odéon

    NOT_YET_RECRUITING

    Paris, 75006, France

  • Centre Rétine Gallien

    RECRUITING

    Bordeaux, 33000, France

  • Centre médico-chirurgical de Touraine

    RECRUITING

    Tours, 37540, France

  • Chichua Medical Centre Mzera LLC

    WITHDRAWN

    Tbilisi, Georgia

  • Cumberland Valley Retina Consultants

    SUSPENDED

    Hagerstown, Maryland, 21740, United States

  • Dietrich Bonhoeffer Klinikum

    RECRUITING

    Neubrandenburg, 17036, Germany

  • Hadassah Medical Center

    RECRUITING

    Jerusalem, 9112001, Israel

  • Hopital de La Croix-Rousse Service D'Ophtalmologie Groupement Hospitalier Nord Hospices Civils de Lyon

    RECRUITING

    Lyon, 69317, France

  • Institute of Eye Surgery (IOES Waterford)

    RECRUITING

    Waterford, X91 DH9W, Ireland

  • Medical Retina & Imaging Unit, IRCCS MultiMedica, Ospedale San Giuseppe

    RECRUITING

    Milan, Milano, 20123, Italy

  • Medizinische Hochschule Hannover Augenklinik

    NOT_YET_RECRUITING

    Hanover, 30625, Germany

  • Ophthalmological Center After S.V. Malayan

    RECRUITING

    Yerevan, 0048, Armenia

  • Retina-Vitreous Associates Medical Group

    RECRUITING

    Beverly Hills, California, 90211, United States

  • Tel Aviv Medical Center

    RECRUITING

    Tel Aviv, 6423906, Israel

  • UNIVERSITÄTSKLINIKUM ULM Klinik für Augenheilkunde

    NOT_YET_RECRUITING

    Ulm, 89075, Germany

  • UOS Retina Medica, P.O. Britannico, IRCCS Fondazione G.B. Bietti per lo Studio e la Ricerca in OftalmologiaUOS Retina Medica, P.O. Britannico, IRCCS Fondazione G.B. Bietti per lo Studio e la Ricerca in Oftalmologia

    RECRUITING

    Roma, Roma, 00184, Italy

  • UPMC Kildare Hospital Prosperous Rd Clane, Kildare Ireland

    NOT_YET_RECRUITING

    Kildare, W91 W535, Ireland

  • Unità di Oculistica, IRCCS Ospedale San Raffaele

    RECRUITING

    Milan, Milano, 20132, Italy

  • Universitäts-Augenklinik Bonn

    RECRUITING

    Bonn, 53127, Germany

  • Universitätsklinikum Freiburg Klinik für Augenheilkunde

    RECRUITING

    Freiburg im Breisgau, 79106, Germany

  • Universitätsklinikum Tübingen, Department für Augenheilkunde.

    NOT_YET_RECRUITING

    Tübingen, 72076, Germany

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