New MRI dye shows promise in japanese patients

NCT ID NCT06010173

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 3 trial tested gadopiclenol, a new MRI contrast agent, in 240 Japanese adults and children with known or suspected lesions in the brain or body. The study compared a lower dose of gadopiclenol to a standard dose of gadobutrol to see if it could provide equally clear images. The goal was to improve MRI safety by using less contrast material.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gadopiclenol (MRI contrast agent)

What this could lead to

If successful, this could confirm that a lower dose of gadopiclenol works as well as the standard contrast agent for MRI scans in Japanese patients.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. The study only included Japanese participants, so findings may not apply to other populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fukuoka University Hospital

    Fukuoka, 814-0180, Japan

  • Gifu University Hospital

    Gifu, 501-1194, Japan

  • Gunma University Hospital

    Gunma, 371-8511, Japan

  • Hamamatsu University Hospital

    Shizuoka, 431-3192, Japan

  • Hiroshima City Hiroshima Citizens Hospital

    Hiroshima, 730-8518, Japan

  • Jichi Medical University Hospital

    Tochigi, 329-0498, Japan

  • Kanagawa Children's Medical Center

    Kanagawa, 232-0066, Japan

  • Kawasaki Medical School Hospital

    Okayama, 701-0192, Japan

  • Kobe City Medical Center General Hospital

    Kobe, 650-0047, Japan

  • Kurobe City Hospital

    Toyama, 938-8502, Japan

  • Kyoto City Hospital

    Kyoto, 604-8845, Japan

  • Meitetsu Hospital

    Aichi, 451-8511, Japan

  • Nakamura Memorial Hospital

    Hokkaido, 060-8570, Japan

  • Nara Medical University Hospital

    Nara, 634-8522, Japan

  • National Center for Child Health and Development

    Tokyo, 157-8535, Japan

  • National Hospital Organization Shikoku Medical Center for Children and Adults

    Kagawa, 765-8507, Japan

  • Osaka Metropolitan University Hospital

    Osaka, 545-8586, Japan

  • Saitama Prefectural Children's Medical Center

    Saitama, 330-8777, Japan

  • Shin-Kuki General Hospital

    Saitama, 346-0021, Japan

  • Shizuoka General Hospital

    Shizuoka, 420-8527, Japan

  • Toho University Omori Medical Center

    Tokyo, 143-8541, Japan

  • Tohoku University Hospital

    Miyagi, 980-8574, Japan

  • Tokyo Metropolitan Children's Medical Center

    Tokyo, 183-8561, Japan

  • Tokyo Shinagawa Hospital

    Tokyo, 140-8522, Japan

  • Tominaga Hospital

    Osaka, 556-0017, Japan

  • University Hospital, Kyoto Prefectural University of Medicine

    Kyoto, 602-8566, Japan

  • Yamaguchi University Hospital

    Yamaguchi, 755-8505, Japan