New pill tested to slow scarring in damaged kidneys

NCT ID NCT05213624

Summary

This study tested whether a new oral medicine called BI 764198 could help control a serious kidney disease called focal segmental glomerulosclerosis (FSGS). For about 3 months, 67 adult participants took either one of three different doses of the medicine or a placebo pill. Researchers measured kidney health primarily by checking for a reduction in protein in the participants' urine, which is a key sign of kidney damage.

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Contacts and locations

Locations

  • A.O. Policlinico Giovanni XXIII di Bari

    Bari, 70124, Italy

  • Addenbrooke's Hospital

    Cambridge, CB2 0QQ, United Kingdom

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Dallas Nephrology Associates Medical Clinic

    DeSoto, Texas, 75115-2011, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Dunedin Hospital

    Dunedin, 9016, New Zealand

  • Elixia Fort Lauderdale, LLC

    Fort Lauderdale, Florida, 33308, United States

  • Emory Children's Center

    Atlanta, Georgia, 30322, United States

  • Fondazione Salvatore Maugeri

    Pavia, 27100, Italy

  • Fu Yang people's Hospital

    Fuyang, 236000, China

  • Fundació Puigvert

    Barcelona, 08025, Spain

  • Griffith Health

    Southport, Queensland, 4125, Australia

  • Guangdong Provincial People's Hospital

    Guangzhou, 510080, China

  • HOP Bicêtre

    Le Kremlin-Bicêtre, 94270, France

  • HOP Hôtel-Dieu

    Nantes, 44093, France

  • HOP Pellegrin

    Bordeaux, 33076, France

  • Hospital Clínic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Germans Trias i Pujol

    Badalona, 08916, Spain

  • Hospital Universitari Vall D Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital del Mar

    Barcelona, 08003, Spain

  • Jacobi Medical Center

    The Bronx, New York, 10461, United States

  • Liverpool Hospital

    Liverpool, New South Wales, 2170, Australia

  • Medizinische Hochschule Hannover

    Hanover, 30625, Germany

  • NANI Research, LLC

    Oak Brook, Illinois, 60523, United States

  • Nephrology Consultants, LLC

    Huntsville, Alabama, 35805, United States

  • New Zealand Clinical Research (ChristChurch)

    Christchurch, 8011, New Zealand

  • Policlinico S. Orsola-Malpighi

    Bologna, 40138, Italy

  • Prolato Clinical Research Center-Houston-68087

    Houston, Texas, 77054, United States

  • Royal Brisbane and Women's Hospital

    Herston, Queensland, 4029, Australia

  • Salford Royal

    Salford, M6 8HD, United Kingdom

  • Shanghai Fifth People's Hospital affiliated to Fudan University

    Shanghai, 200240, China

  • South Florida Research Institute

    Lauderdale Lakes, Florida, 33313, United States

  • St Luke's Hospital

    Bradford, BD5 0NA, United Kingdom

  • Sunshine Hospital

    AT Albans, Victoria, 3021, Australia

  • Texas Tech University Health Sciences Center-Amarillo-63885

    Amarillo, Texas, 79106, United States

  • The First Affiliated Hospital of Nanchang University

    Nanchang, 330006, China

  • The First Afiliated Hospital, Sun Yet-sen University

    Guangzhou, 510080, China

  • The First People's Hospital of Nanning

    Nanning, 530000, China

  • The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

    Torrance, California, 90502, United States

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States

  • The University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Tongren hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, 200051, China

  • Total Research Group, LLC

    Miami, Florida, 33126, United States

  • UZ Leuven

    Leuven, 3000, Belgium

  • University of California San Francisco

    San Francisco, California, 94121, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Universitätsklinikum Heidelberg

    Heidelberg, 69120, Germany

  • Universitätsklinikum Köln (AöR)

    Cologne, 50937, Germany

  • Valiance Clinical Research-South Gate-67878

    South Gate, California, 90280-5219, United States

  • Valiance Clinical Research-Tarzana-68237

    Tarzana, California, 91356, United States

  • Westmead Hospital

    Westmead, New South Wales, 2145, Australia

  • Zhejiang Province People's Hospital

    Hangzhou, 310014, China

Conditions

Explore the condition pages connected to this study.