New cocktail targets Hard-to-Treat stomach cancer

NCT ID NCT07334431

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a combination of three drugs (fruquintinib, trastuzumab, and chemotherapy) as a first treatment for people with HER2-positive advanced stomach or gastroesophageal junction cancer. The goal is to see if the combo is safe and can shrink tumors or slow cancer growth. About 45 participants will take part in this early-phase trial at one hospital in China.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fruquintinib, trastuzumab, oxaliplatin, capecitabine

What this could lead to

If it works, this could offer a new first-line treatment option for people with HER2-positive advanced stomach cancer, potentially shrinking tumors and delaying disease progression.

What could go wrong

This is an early-phase, small study (45 people) at one center. The drug combo may cause significant side effects, and results may not apply to everyone. Success is not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer gastric neoplasm gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Henan Cancer Hospital (Affiliated Cancer Hospital of Zhengzhou University)

    RECRUITING

    Zhengzhou, Henan, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact