Poop pills could help kids with colitis stay healthy

NCT ID NCT05202990

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether frozen stool capsules (fecal transplants) can help children aged 8-17 with ulcerative colitis stay in remission after steroid treatment. Participants will receive either capsules or enemas containing healthy donor stool. The main goal is to see if the capsules increase gut bacteria diversity at 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Fecal microbiota transplantation (FMT) via frozen stool capsules
What this could lead to
If successful, this could offer a less invasive way to maintain remission in children with ulcerative colitis by restoring healthy gut bacteria.
What could go wrong
This is a small early-phase trial with only 26 participants, so results may not apply broadly. The treatment involves colonoscopy and swallowing many capsules, which some children may find difficult.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Pediatric Gastroenterology, Hepatology and Nutrition - Necker - Enfants Malades Hospital

    Paris, 75015, France

  • Department of Pediatric Gastroenterology, Robert Debré Hospital

    Paris, 75019, France

  • Department of gastroenterology, Armand Trousseau Hospital

    Paris, 75012, France