Can a donor lens implant restore clarity to clouded corneas?
NCT ID NCT04642729
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial investigates whether implanting a fresh corneal lenticule — a thin layer of donor cornea taken from myopic patients — can improve transparency and vision in people with macular corneal dystrophy, a condition that clouds the cornea. Using a femtosecond laser, surgeons remove damaged tissue and replace it with a healthy lenticule carrying live keratocytes. The study will measure changes in corneal clarity and visual acuity over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fresh corneal lenticule implantation using Relex-Smile surgery
- What this could lead to
- If it works, this could offer a new way to restore corneal clarity and vision in people with macular corneal dystrophy, potentially reducing the need for full corneal transplants.
- What could go wrong
- This is a very small, early-stage trial with only 15 participants. The procedure is experimental, and risks include infection, graft rejection, or no improvement in vision.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eye Hospital Pristina
Pristina, 10000, Kosovo