Cure My Disease

Don't miss your cure!

 Log in / Sign up

Laser vs freeze: oral surgery showdown aims to reduce stress and pain

NCT ID NCT07708389

Disease control Sponsor: Kutahya Health Sciences University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study compares two methods for treating a lip-tie (a tight band of tissue connecting the upper lip to gums): a diode laser and liquid nitrogen cryotherapy. Researchers measure stress hormone levels in saliva and track pain, swelling, and healing in 40 adults. The goal is to see which technique leads to a smoother recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
970-nm diode laser frenectomy or liquid nitrogen cryotherapy
What this could lead to
If one method proves less stressful and speeds healing, it could become the preferred technique for this common oral procedure.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. Both procedures carry risks like pain, swelling, or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years. * Systemically healthy, ASA I status. * Clinical indication for maxillary labial frenectomy. * Ability to attend postoperative follow-up visits. * Provision of written informed consent. Exclusion Criteria: * Systemic or local corticosteroid use within the last 6 months. * Endocrine disease that may affect cortisol levels. * Pregnancy or lactation. * Active oral infection. * Chronic analgesic or anti-inflammatory drug use. * Psychiatric medication use. * Smoking. * ASA II or higher systemic status. * Inability to attend follow-up visits. * Refusal to participate in the study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Hypertrophic maxillary labial frenulum are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypertrophic maxillary labial frenulum Maxillary labial frenulum abnormality

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Kutahya Health Sciences University Faculty of Dentistry

    Kütahya, Kütahya, 43020, Turkey (Türkiye)