New drug trial aims to tame muscle stiffness in rare disease
NCT ID NCT06667453
First seen Jan 11, 2026 · Last updated May 06, 2026 · Updated 24 times
Summary
This study tests an experimental drug called PGN-EDODM1 in 24 adults with myotonic dystrophy type 1 (DM1), a condition that causes muscle stiffness and weakness. The main goal is to see if the drug is safe and tolerable compared to a placebo. Researchers will also measure how the drug moves through the body and look for changes in muscle tissue.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CIUSSS du Saguenay-Lac-Saint-Jean
RECRUITINGChicoutimi, Quebec, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Montreal Neurological Institute
RECRUITINGMontreal, Quebec, H3A 2B4, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Newcastle Upon Tyne Hospitals
RECRUITINGNewcastle upon Tyne, NE7 7DN, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ottawa Hospital Research Institute (OHRI)
RECRUITINGOttawa, Ontario, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pacific Clinical Research Network Auckland
ACTIVE_NOT_RECRUITINGTakapuna, Auckland, 0622, New Zealand
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Salford Royal Hospital
RECRUITINGSalford, England, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University College London Hospitals NHS Foundation Trust
RECRUITINGLondon, UK, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Calgary
RECRUITINGCalgary, Alberta, T2N 4Z6, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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