New hope for teens with fragile x: drug trial targets learning and behavior

NCT ID NCT05163808

Summary

This study tested an investigational drug, BPN14770, to see if it could improve thinking skills, language, and daily functioning in male adolescents with Fragile X Syndrome. It involved 163 boys aged 9 to 18 and compared the drug's effects to a placebo over 13 weeks. The main goal was to measure changes in cognitive and behavioral scores reported by caregivers and clinicians.

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Contacts and locations

Locations

  • Amnova Clinical Research

    Irvine, California, 92604, United States

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinatti Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Clinic for Special Children

    Strasburg, Pennsylvania, 17579, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322, United States

  • Greenwood Genetic Center

    Greenville, South Carolina, 29605, United States

  • Icahn School of Medicine at Mount Sinai Hospital

    New York, New York, 10029, United States

  • Kennedy Krieger Institute

    Baltimore, Maryland, 21205, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Suburban Research Associates

    Media, Pennsylvania, 19063, United States

  • Thompson Autism & Neurodevelopment Center - CHOC

    Orange, California, 92868, United States

  • U Mass

    Worcester, Massachusetts, 01655, United States

  • UC Davis

    Sacramento, California, 95817, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Utah and Primary Childrens Hospital

    Salt Lake City, Utah, 84113, United States

Conditions

Explore the condition pages connected to this study.