Spinal anesthesia study aims to reduce dangerous blood pressure drops
NCT ID NCT07616882
First seen Jun 02, 2026 · Last updated Jun 22, 2026 · Updated 3 times
Summary
This phase 2 trial will test whether giving the anesthetic bupivacaine in two smaller doses (fractionated) instead of one large dose (bolus) leads to more stable blood pressure during spinal anesthesia for lower limb surgery. The study plans to enroll 100 adults aged 18-60 who are healthy or have mild systemic disease. Researchers will measure blood pressure changes and track any need for medication to treat low blood pressure.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEMONDYNAMIC CHANGES IN SPINAL ANESTHESIA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Liaquat National Hospital
Karachi, Sindh, 74000, Pakistan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine (spinal anesthetic)
What this could lead to
If successful, this could point toward a safer way to give spinal anesthesia that reduces sudden drops in blood pressure during surgery.
What could go wrong
This is a small, early-phase study (100 people) that only looks at blood pressure changes, not long-term outcomes. Results may not apply to all patients or surgeries.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.