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New hope for kids with drug-resistant HIV: experimental combo shows promise

NCT ID NCT04648280

Ongoing Disease control Sponsor: PENTA Foundation Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This study tests a new HIV drug called fostemsavir in children and teens (ages 6 to 17) whose current HIV medicines are no longer working because the virus has become resistant. The drug is given along with other tailored HIV medicines. The goal is to see if it is safe and can lower the amount of virus in the blood. About 60 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • FAM-CRU

    Cape Town, South Africa

  • Hospital Federal dos Servidores do Estado

    Rio de Janeiro, 20221-161, Brazil

  • Hospital Geral de Nova Iguaçu

    Nova Iguaçu, Brazil

  • King Edward VIII Hospital

    Durban, South Africa

  • PHRU

    Soweto, South Africa

  • Rahima Moosa Mother and Child Hospital

    Johannesburg, 2112, South Africa

  • Wits Reproductive Health and HIV Institutel

    Johannesburg, South Africa

Conditions

Explore the condition pages connected to this study.

HIV INFECTIONS WITH MULTI DRUG RESISTANT VIRUS