New heart drug trial aims to help patients breathe easier

NCT ID NCT07023614

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 21 times

Summary

This study tests an experimental drug called ninerafaxstat in 165 people with a type of thickened heart muscle that makes it hard to breathe and exercise. Participants will receive either the drug or a placebo on top of their usual care. The main goal is to see if the drug improves symptoms and quality of life over several months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Imbria Investigational Site

    RECRUITING

    La Jolla, California, 92037, United States

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  • Imbria Investigational Site

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    Los Angeles, California, 90048, United States

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  • Imbria Investigational Site

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    San Francisco, California, 94143, United States

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  • Imbria Investigational Site

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    Washington D.C., District of Columbia, 20010, United States

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  • Imbria Investigational Site

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    Miami, Florida, 33136, United States

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  • Imbria Investigational Site

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    Chicago, Illinois, 60611, United States

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  • Imbria Investigational Site

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    Boston, Massachusetts, 02114, United States

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  • Imbria Investigational Site

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    Burlington, Massachusetts, 01805, United States

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  • Imbria Investigational Site

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    Grand Rapids, Michigan, 49503, United States

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  • Imbria Investigational Site

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    Rochester, Minnesota, 55905, United States

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  • Imbria Investigational Site

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    St Louis, Missouri, 63110, United States

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  • Imbria Investigational Site

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    New York, New York, 10016, United States

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  • Imbria Investigational Site

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    Charlotte, North Carolina, 28204, United States

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  • Imbria Investigational Site

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    Portland, Oregon, 97239, United States

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  • Imbria Investigational Site

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    Philadelphia, Pennsylvania, 19104, United States

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  • Imbria Investigational Site

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    Houston, Texas, 77030, United States

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  • Imbria Investigational Site

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    Plano, Texas, 75093, United States

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  • Imbria Investigational Site

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    Charlottesville, Virginia, 22903, United States

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  • Imbria Investigational Site

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    Graz, 8036, Austria

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  • Imbria Investigational Site

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    Edegem, 2650, Belgium

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  • Imbria Investigational Site

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    Montpellier, 34090, France

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  • Imbria Investigational Site

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    Paris, 75015, France

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  • Imbria Investigational Site

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    Saint-Herblain, 44800, France

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  • Imbria Investigational Site

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    Bad Oeynhausen, 32545, Germany

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  • Imbria Investigational Site

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    Göttingen, 37075, Germany

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  • Imbria Investigational Site

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    Heidelberg, 69120, Germany

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  • Imbria Investigational Site

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    Florence, 50134, Italy

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  • Imbria Investigational Site

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    Milan, 20131, Italy

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  • Imbria Investigational Site

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    Naples, 80131, Italy

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  • Imbria Investigational Site

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    Amsterdam-Zuidoost, 1105 AZ, Netherlands

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  • Imbria Investigational Site

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    Rotterdam, 3015 GD, Netherlands

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  • Imbria Investigational Site

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    Katowice, 40-555, Poland

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  • Imbria Investigational Site

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    Warsaw, 02-507, Poland

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  • Imbria Investigational Site

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    Wroclaw, 50-981, Poland

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  • Imbria Investigational Site

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    Guimarães, 4835-044, Portugal

    Contact

  • Imbria Investigational Site

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    Lisbon, 1169-024, Portugal

    Contact

  • Imbria Investigational Site

    RECRUITING

    Lisbon, 1500-650, Portugal

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  • Imbria Investigational Site

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    Barcelona, Barcelona, 08035, Spain

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  • Imbria Investigational Site

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    A Coruña, Galicia, 15006, Spain

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  • Imbria Investigational Site

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    Madrid, Madrid, 28034, Spain

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  • Imbria Investigational Site

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    Vigo, Pontevedra, 36312, Spain

    Contact

  • Imbria Investigational Site

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    Seville, Sevilla, 41009, Spain

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  • Imbria Investigational Site

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    Seville, Sevilla, 41013, Spain

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  • Imbria Investigational Site

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    Barcelona, 8036, Spain

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  • Imbria Investigational Site

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    Barcelona, 8041, Spain

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  • Imbria Investigational Site

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    Barcelona, 8907, Spain

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  • Imbria Investigational Site

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    El Palmar, 30120, Spain

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  • Imbria Investigational Site

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    Madrid, 28034, Spain

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  • Imbria Investigational Site

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    Palma de Mallorca, 7198, Spain

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  • Imbria Investigational Site

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    Salamanca, 37007, Spain

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  • Imbria Investigational Site

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    Valencia, 46009, Spain

  • Imbria Investigational Site

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    Valencia, 46009, Spain

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  • Imbria Investigational Site

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    London, England, W12 0HS, United Kingdom

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  • Imbria Investigational Site

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    Glasgow, Scotland, G51 4TF, United Kingdom

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  • Imbria Investigational Site

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    London, 401109, United Kingdom

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  • Imbria Investigational Site

    RECRUITING

    London, EC1A 7BE, United Kingdom

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.