New drug trial aims to halt debilitating 'Second Skeleton' disease

NCT ID NCT06508021

Summary

This study is testing an experimental drug called andecaliximab for people with fibrodysplasia ossificans progressiva (FOP), a rare and severe condition where muscles and soft tissues turn into bone. The main goal is to see if the drug can safely reduce the formation of new, abnormal bone growths and lessen painful flare-ups. The trial involves about 92 children and adults and compares the drug against a placebo for up to a year.

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Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • University of California San Francisco (UCSF)

    San Francisco, California, 94143, United States

  • University of Pennsylvania - Perelman Center for Advanced Medicine

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.