Triple therapy aims to turn inoperable bowel cancer into a surgical target

NCT ID NCT07446465

Not yet recruiting Disease control Sponsor: Ye Xu Source: ClinicalTrials.gov ↗

First seen Mar 24, 2026 · Last updated May 15, 2026 · Updated 7 times

Summary

This study tests whether combining chemotherapy (FOLFOX), a targeted drug (fruquintinib), and an immunotherapy (serplulimab) can shrink advanced colorectal cancer enough to allow surgery. About 42 adults with a specific type of colorectal cancer (pMMR/MSS) that cannot be removed initially will receive the combination as their first treatment. The main goals are to see how many tumors become operable and how many shrink significantly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    Shanghai, Xuhui, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.