Engineered immune cells take on tough leukemia in early trial

NCT ID NCT07538713

Not yet recruiting Disease control Sponsor: Qi deng Source: ClinicalTrials.gov ↗

First seen Apr 21, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This early-stage study tests a new type of CAR-T cell therapy (FO33 CAR-T) for people with acute myeloid leukemia (AML) that has come back or not responded to standard treatments. The therapy uses a patient's own immune cells, modified to target the CD33 protein found on most AML cells. The main goals are to check safety and see if the treatment can reduce or eliminate leukemia. About 18 participants will take part in this single-center trial.

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