Poop pills plus chemo: new combo tackles tough colon cancer
NCT ID NCT06801665
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether transplanting healthy gut bacteria (fecal microbiota transplant) can boost the effects of immunotherapy and chemotherapy in 30 people with advanced colon cancer that has spread to the liver. Participants receive the combination for six cycles, then may continue with maintenance therapy. The main goal is to see how many patients' tumors shrink significantly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fecal microbiota transplant (FMT) plus QL1706 (an immunotherapy), bevacizumab, and XELOX chemotherapy
- What this could lead to
- If it works, this could improve tumor shrinkage and delay cancer progression in people with advanced colon cancer that has spread to the liver.
- What could go wrong
- This is a small, early-phase trial with only 30 participants and no comparison group, so results may not apply broadly. Combining multiple treatments also raises the risk of serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED COLON CANCER WITH LIVER METASTASIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Second People's Hospital of Changzhou
RECRUITINGChangzhou, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.