Poop pills could save kids from deadly transplant complication

NCT ID NCT07602751

First seen May 22, 2026 · Last updated May 22, 2026

Summary

This study tests whether fecal microbiota transplantation (FMT) is safe and possible for children and young adults (ages 3 months to 25 years) with severe gut graft-versus-host disease (GVHD) that does not respond to steroids. GVHD is a serious complication after a bone marrow transplant where donor cells attack the patient's body. Participants will receive 1 to 3 FMT treatments via a tube into the intestine. The main goal is to check for side effects, and the study also looks at whether the treatment helps control the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital

    Roma, 00165, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pediatric Hematology and Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna

    Bologna, 40138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UOC Clinica di Oncoematologia Pediatrica, Azienda Ospedale-Università Padova

    Padova, 35128, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.