Which fluid strategy works best after abdominal surgery? new study aims to find out
NCT ID NCT07303855
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two different ways to give fluids through an IV to patients in the ICU after major abdominal surgery. One method uses a measure called cardiac index, and the other uses central venous pressure. The goal is to see which method helps doctors give the right amount of fluids, and whether it affects recovery, time in the ICU, or complications. About 60 adults aged 18 to 65 who are scheduled for elective major abdominal surgery and planned ICU stay will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 18 to 65 years. * Patients with a Body Mass Index (BMI) between 18 and 30 kg/m². * Patients undergoing elective major abdominal surgery with a planned postoperative admission to the ICU. * Patients with an American Society of Anesthesiologists (ASA) physical status classification of I to III. Exclusion Criteria: * Patients with pre-operative cardiovascular disorders (Coronary Artery Disease, or heart failure NYHA Class III and IV). * Patients with severe renal impairment (Chronic Kidney Disease Stage V) with or without hemodialysis and fluid restrictions. * Non-sinus cardiac rhythm. * Pregnancy. * Patients with right heart failure (patients with signs of congestion and symptoms of right heart failure accompanied by evidence of reduced right ventricular function, indicated by TAPSE \< 17 mm). * Patients with pulmonary hypertension (patients with echocardiographic suspicion of tricuspid regurgitation, tricuspid regurgitation velocity \> 3.4 m/s, or mean pulmonary artery pressure \> 20 mmHg from right heart catheterization). * Patients with Acute Respiratory Distress Syndrome (ARDS) or patients requiring specialized ventilation modes. * Patients who refuse to participate in the study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cipto Mangunkusumo Hospital
RECRUITINGJakarta Pusat, DKI Jakarta, 10430, Indonesia