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Brain oxygen and fluids: key to preventing Post-Surgery confusion in seniors?

NCT ID NCT07302061

Knowledge-focused Sponsor: Goztepe Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how the type of anesthesia (general vs. spinal) and fluid levels during leg surgery affect thinking problems in people over 65. Researchers will monitor brain oxygen levels and fluid status during surgery, then test memory and thinking 24 and 48 hours later. The goal is to find ways to prevent confusion after surgery in older patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors choose anesthesia methods and monitor fluid levels to reduce confusion after surgery in older patients.
What could go wrong
This is a small, early-stage observational study, not a treatment trial. It may not lead to clear recommendations, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Aug 2025

Expected to finish

Jan 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing Lower extremity surgery

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over the age of 65 * Patients with an American Society of Anesthesiologists (ASA) score of II-III * Patients with a Mini Mental State Examination (MMSE) score of ≥24 on the first day before surgery Exclusion Criteria: * Patients with coagulation disorders * Patients with a history of anticoagulant medication use * Patients with advanced organ failure * Patients with Alzheimer's disease or advanced dementia * Patients with allergies to the medications used in the study * Mental Retardation * Patients with a wound infection at the site of spinal anesthesia * Patients with a history of cerebrovascular hemorrhage * Patients who did not consent;

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative cognitive deficit (POCD)

Contacts and locations

Locations

  • Goztepe training and research hospital

    Istanbul, Kadikoy, 34744, Turkey (Türkiye)