Scientists to peek inside tonsils after nasal flu vaccine
NCT ID NCT07093281
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will give the nasal flu vaccine to 25 people who are already scheduled to have their tonsils or adenoids removed for sleep apnea. Researchers will then study the removed tissue to see how the vaccine affects immune cells near the nose. The goal is to better understand how nasal vaccines work, since they don't cause the same blood changes as shots.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Live attenuated influenza vaccine (nasal spray)
- What this could lead to
- If successful, this could help design better nasal vaccines that boost immunity right where the flu enters the body.
- What could go wrong
- This is a very small, early-stage study (25 people) focused on understanding immune responses, not on treating or preventing disease. Results may not apply to the general population.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Maryland Medical Center
Baltimore, Maryland, 21231, United States