Gene therapy trial tests new approach for rare genetic disorder

NCT ID NCT05324943

Summary

This first-in-human study tested the safety and early effects of a new gene therapy called FLT201 in adults with Gaucher disease type 1. The therapy aims to boost a missing enzyme to help the body break down harmful substances that build up in cells. Six adults who were already on standard treatment participated to see if FLT201 could safely increase enzyme activity and potentially improve their condition.

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Contacts and locations

Locations

  • Hospital Quironsalud Zaragoza

    Zaragoza, Spain

  • Hospital de Clinicas de Porto Alegre (HCPA)

    Porto Alegre, Brazil

  • Kaiser Permanente

    Los Angeles, California, 90027, United States

  • Lysosomal Rare Disorders Research and Treatment Center

    Fairfax, Virginia, 22030-6066, United States

  • Rabin Medical Center - PPDS

    Petah Tikva, Israel

  • Royal Free Hospital

    London, United Kingdom

  • Salford Royal Hospital

    Salford, United Kingdom

  • Shaare Zedek Medical Center

    Jerusalem, Israel

  • SphinCS

    Höchheim, Germany

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, Israel

Conditions

Explore the condition pages connected to this study.