Could a simple scan replace bone marrow biopsies for leukemia patients?

NCT ID NCT02392429

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 23 times

Summary

This study looks at whether a special PET scan using a radioactive tracer called FLT can help doctors quickly tell if chemotherapy is working in patients with newly diagnosed acute myeloid leukemia (AML). About 87 adults with AML will receive the FLT injection and undergo a PET/CT scan after starting treatment. The goal is to see if the scan can predict remission as accurately as the standard bone marrow biopsy, which is more invasive and uncomfortable.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • UT Southwestern/Simmons Cancer Center-Dallas

    Dallas, Texas, 75390, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University/Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.