New device shows promise for treating dangerous lung clots

NCT ID NCT03761173

Completed Disease control Sponsor: Inari Medical Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at a device called the FlowTriever, which is used to remove blood clots from the lungs in people with a serious condition called acute pulmonary embolism. Researchers followed 1,200 patients to see how safe and effective the device was in real-world use. The goal was to track major problems like death, major bleeding, or injury to the lungs or heart within 48 hours of the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FlowTriever System (a device to remove blood clots from lung arteries) and anticoagulation medication
What this could lead to: If successful, this could confirm that the FlowTriever device is a safe and effective way to treat acute pulmonary embolism, potentially reducing complications and improving recovery.
What could go wrong: This is a registry study, not a randomized trial, so results may be influenced by patient selection. The device carries risks like bleeding or injury to blood vessels, and it may not work for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism Thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PE - PULMONARY EMBOLISM PE - PULMONARY THROMBOEMBOLISM

Contacts and locations

Locations

Albany Medical Center

Albany, New York, 12208, United States
Allgemeines Krankenhaus AKH Wien

Vienna, Austria
Ascension Genesys Hospital

Grand Blanc, Michigan, 48439, United States
Ascension Providence Hospital

Madison Heights, Michigan, 48334, United States
Ascension Providence Rochester Hospital

Rochester, Michigan, 48307, United States
Ascension Sacred Heart

Pensacola, Florida, 32504, United States
Aurora St. Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
Baptist Health Lousville

Louisville, Kentucky, 40207, United States
Beaumont Health

Royal Oak, Michigan, 48073, United States
CHU Grenoble

Grenoble, France
CardioVoyage

Denison, Texas, 75071, United States
Cardioangiologisches Centrum Bethanien

Frankfurt, Germany
CentraCare Heart & Vascular Center

Saint Cloud, Minnesota, 56303, United States
Centre Hospitalier Universitaire de Besançon

Besançon, France
Charité Hospital - Campus Virchow-Klinikum

Berlin, Germany
Christiana Care Health Services

Newark, Delaware, 19713, United States
Emory University

Atlanta, Georgia, 30308, United States
European Hospital Georges Pompidou

Paris, France
Gregorio Maranon University Hospital

Madrid, Spain
HCL Hôpital Louis Pradel - Hôpital Cardiologique

Lyon, France
Helios Kliniken Schwerin

Schwerin, Germany
Henry Ford Health System

Detroit, Michigan, 48202, United States
Hopital de la Cavale Blanche - CHU Brest

Brest, France
Hospital Clínico San Carlos

Madrid, 28040, Spain
Indiana University School of Medicine

Indianapolis, Indiana, 46202, United States
Inova Fairfax

Falls Church, Virginia, 22042, United States
Inselspital

Bern, Switzerland
Institut Coeur Poumon - CHU de Lille

Lille, France
Jamaica Hospital

Queens, New York, 11418, United States
Javon Bea Hospital

Rockford, Illinois, 61103, United States
Kantonsspital Sankt Gallen

Sankt Gallen, Switzerland
Lakeland Vascular Institute

Lakeland, Florida, 33801, United States
Lexington Medical Center

West Columbia, South Carolina, 29169, United States
Memorial Hospital Jacksonville

Jacksonville, Florida, 32216, United States
Methodist Healthcare Foundation

Germantown, Tennessee, 38138, United States
Metropolitan Heart and Vascular Institute

Minneapolis, Minnesota, 55433, United States
Missouri Cardiovascular Specialists

Columbia, Missouri, 65201, United States
Mount Sinai

New York, New York, 10029, United States
Mount Sinai Medical Center of Florida

Miami, Florida, 33140, United States
NYU Langone Medical Center

New York, New York, 10016, United States
Northwell Health

Manhasset, New York, 11030, United States
Northwestern University

Evanston, Illinois, 60208, United States
Norton Healthcare

Louisville, Kentucky, 40205, United States
Opelousas General

Opelousas, Louisiana, 70570, United States
Palmetto General Hospital

Miami, Florida, 33016, United States
Pima Heart and Vascular

Tucson, Arizona, 85741, United States
Providence Regional Medical Center Everett

Everett, Washington, 98201, United States
Providence Sacred Heart

Spokane, Washington, 99204, United States
Rush Medical Center

Chicago, Illinois, 60612, United States
SUNY, The University at Buffalo

Buffalo, New York, 14203, United States
Saint Luke's Hospital of Kansas City

Lee's Summit, Missouri, 64086, United States
Sarasota Memorial Hospital

Sarasota, Florida, 34239, United States
Sentara

Norfolk, Virginia, 23507, United States
St. Francis Hospital & Heart Center

Roslyn, New York, 11576, United States
St. Joseph Mercy

Ypsilanti, Michigan, 48106, United States
St. Thomas West

Nashville, Tennessee, 37205, United States
Tallahassee Memorial Hospital

Tallahassee, Florida, 32308, United States
The Royal Free Hospital

London, United Kingdom
The Royal London Hospital, Bart's Health

London, United Kingdom
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
UAB Division of Cardiovascular Disease

Birmingham, Alabama, 35294, United States
UTMC Knoxville

Knoxville, Tennessee, 37920, United States
UZ Antwerpen

Antwerp, Belgium
UZ Brussel

Brussels, Belgium
Unispital

Zurich, Switzerland
Universitair Medisch Centrum Utrecht

Utrecht, Netherlands
Universitatsklinikum des Saarlandes

Homburg, Germany
University Hospital

Heidelberg, Germany
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Arizona College of Medicine

Tucson, Arizona, 85719, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Colorado

Aurora, Colorado, 80045, United States
University of Miami

Miami, Florida, 33125, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of Missouri, Columbia

Columbia, Missouri, 65212, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States
Valley Health

Ridgewood, New Jersey, 07450, United States
Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, 27157, United States
Westchester Medical Center

Valhalla, New York, 10595, United States
Yale University

New Haven, Connecticut, 06511, United States

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