New pill shows promise in shrinking spleens for myelofibrosis patients

NCT ID NCT07317700

Recruiting now Disease control Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd Source: ClinicalTrials.gov ↗

First seen Jan 09, 2026 · Last updated Apr 25, 2026 · Updated 22 times

Summary

This study tests a new drug, flonoltinib maleate, in people with intermediate- or high-risk myelofibrosis, a rare bone marrow disorder. The main goal is to see if the drug can shrink an enlarged spleen by at least 35% and reduce symptoms like pain and fatigue. About 105 participants will be randomly assigned to receive either the new drug or an existing treatment, and they will continue taking it as long as it helps.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (IHCAMS)
RECRUITING

Tianjin, Tianjin Municipality, 300052, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
West China Hospital Sichuan University
RECRUITING

Chengdu, Sichuan, China

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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MF