Fish oil as a depression booster? new trial investigates
NCT ID NCT07645807
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a special fish oil supplement (CreNeuroS) to the antidepressant escitalopram helps reduce depression symptoms more than escitalopram alone. Eighty adults with moderate to severe major depressive disorder will take either the fish oil or a placebo for 8 weeks. Researchers will measure changes in depression scores using the Hamilton Depression Rating Scale.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CreNeuroS CNS fish oil plus softgels (a dietary supplement) combined with escitalopram (an antidepressant)
- What this could lead to
- If it works, this could point toward a simple, natural supplement to boost the effects of standard antidepressants for people with major depression.
- What could go wrong
- This is a small, early-stage trial with only 80 participants. The fish oil may not provide any additional benefit over the antidepressant alone, and results may not apply to everyone with depression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Jupiter Hospital and Research Centre
Vadodara, Gujarat, 390012, India