Engineered immune cells take on hard-to-treat bone cancer in early trial

NCT ID NCT07227571

First seen Nov 12, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This early-stage trial is testing a new treatment called FH-FOLR1 ST CAR T cells for people with advanced osteosarcoma (a type of bone cancer) that has come back or not responded to standard therapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recognize and attack cancer cells, and then infusing them back into the patient. The main goals are to find the safest dose and to see if the treatment can shrink tumors or slow the cancer's growth.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington/Seattle Children's Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

Conditions

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