Triple-Drug attack shows promise for Tough-to-Treat melanoma

NCT ID NCT06594991

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 31 times

Summary

This study tests whether a combination of three drugs (fianlimab, cemiplimab, and ipilimumab) is safe and effective for people with advanced melanoma that no longer responds to standard immunotherapy. About 88 adults with locally advanced or metastatic melanoma will participate. The goal is to see if the tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-••••

  • Hackensack Meridian Health (Data Collection Only)

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-••••

  • Hartford Healthcare Alliance (Data Collection Only)

    NOT_YET_RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact Phone: •••-•••-••••

  • MD Anderson Cancer Center (Data Collection Only)

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Stanford University (Data Collection Only)

    RECRUITING

    Stanford, California, 94305, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.