New hormone combo may help young women beat early uterine cancer without losing fertility

NCT ID NCT05247268

First seen Jun 07, 2026 · Last updated Jun 16, 2026 · Updated 4 times

Summary

This study tests whether a combination of two hormone drugs (GnRHa and letrozole) works better than standard hormone pills (megestrol or medroxyprogesterone) for treating early-stage endometrial cancer while preserving the ability to have children. About 104 women with stage I, low-grade cancer who wish to keep their fertility will be enrolled. The main goal is to see if more women achieve complete cancer remission within 16 weeks with the new combination.

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Contacts and locations

Locations

  • Obstetrics and Gynecology Hospital, Fudan University

    RECRUITING

    Shanghai, 200011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.