New drug combo offers hope for Hard-to-Treat liver disease

NCT ID NCT05749822

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 17 times

Summary

This study is for adults with primary biliary cholangitis (PBC) and compensated cirrhosis who still have high alkaline phosphatase levels despite taking ursodeoxycholic acid (UDCA). Researchers want to see if adding fenofibrate to UDCA can normalize liver enzyme levels and improve symptoms like itching and fatigue. About 104 participants will be followed for up to 36 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Henan Provincial People's Hospital

    RECRUITING

    Zhengzhou, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jiangsu Province Hospital

    RECRUITING

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-••••

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen Memorial Hospital

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of China Medical University

    RECRUITING

    Shenyang, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Third Central Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xiangya Hospital Central South University

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xijing Hospital

    RECRUITING

    Xi'an, Shaanxi, China

    Contact

  • Yan'an University Affiliated Hospital

    RECRUITING

    Yan’an, Shaanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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