New MS drug shows promise in reducing brain lesions

NCT ID NCT05119569

First seen Nov 11, 2025 · Last updated Jun 13, 2026 · Updated 23 times

Summary

This study tests whether fenebrutinib can reduce brain damage in people with relapsing multiple sclerosis (MS). About 109 participants will receive either the drug or a placebo, and brain scans will be used to measure new lesions over 12 weeks. The goal is to see if fenebrutinib can control disease activity, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Lou Ruvo

    Las Vegas, Nevada, 89106, United States

  • Clinical Center Nis

    Niš, 18000, Serbia

  • Clinical Center of Serbia

    Belgrade, 11000, Serbia

  • Clinical Hospital Center Rijeka - PPDS

    Rijeka, 51000, Croatia

  • Clinical Hospital Centre Zemun

    Zemun, 11080, Serbia

  • Clinical center Kragujevac

    Kragujevac, 34000, Serbia

  • Fakultni nemocnice Hradec Kralove

    Hradec Králové, 500 05, Czechia

  • Fakultni nemocnice u sv. Anny v Brne

    Brno, 656 91, Czechia

  • Fullerton Neurology and Headache Center

    Fullerton, California, 92835, United States

  • General Hospital Varazdin

    Varaždin, 42000, Croatia

  • Klinicki bolnicki centar Zagreb

    Zagreb, 10000, Croatia

  • Military Medical Academy

    Belgrade, 11040, Serbia

  • Nemocnice Jihlava

    Jihlava, 58633, Czechia

  • Poliklinika Solmed

    Zagreb, 10000, Croatia

  • University Clinical Centre of the Republic of Srpska

    Banja Luka, 78000, Bosnia and Herzegovina

  • Univerzitna nemocnica Bratislava

    Bratislava, 821 01, Slovakia

  • Vseobecna Fakultni Nemocnice V Praze - CRC - PPDS

    Prague, 128 08, Czechia

Conditions

Explore the condition pages connected to this study.