Promising new pill may slow MS brain damage

NCT ID NCT05119569

First seen Nov 11, 2025 · Last updated Apr 28, 2026 · Updated 18 times

Summary

This study tests an experimental drug called fenebrutinib in people with relapsing multiple sclerosis (RMS). The goal is to see if it can reduce new brain lesions seen on MRI scans compared to a placebo. About 109 participants will take either the drug or a placebo for 12 weeks, with an option to continue in an open-label phase. The study is active but no longer recruiting new participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Lou Ruvo

    Las Vegas, Nevada, 89106, United States

  • Clinical Center Nis

    Niš, 18000, Serbia

  • Clinical Center of Serbia

    Belgrade, 11000, Serbia

  • Clinical Hospital Center Rijeka - PPDS

    Rijeka, 51000, Croatia

  • Clinical Hospital Centre Zemun

    Zemun, 11080, Serbia

  • Clinical center Kragujevac

    Kragujevac, 34000, Serbia

  • Fakultni nemocnice Hradec Kralove

    Hradec Králové, 500 05, Czechia

  • Fakultni nemocnice u sv. Anny v Brne

    Brno, 656 91, Czechia

  • Fullerton Neurology and Headache Center

    Fullerton, California, 92835, United States

  • General Hospital Varazdin

    Varaždin, 42000, Croatia

  • Klinicki bolnicki centar Zagreb

    Zagreb, 10000, Croatia

  • Military Medical Academy

    Belgrade, 11040, Serbia

  • Nemocnice Jihlava

    Jihlava, 58633, Czechia

  • Poliklinika Solmed

    Zagreb, 10000, Croatia

  • University Clinical Centre of the Republic of Srpska

    Banja Luka, 78000, Bosnia and Herzegovina

  • Univerzitna nemocnica Bratislava

    Bratislava, 821 01, Slovakia

  • Vseobecna Fakultni Nemocnice V Praze - CRC - PPDS

    Prague, 128 08, Czechia

Conditions

Explore the condition pages connected to this study.