New drug targets root cause of dangerous kidney disease in lupus patients

NCT ID NCT06064929

Summary

This early-stage study is testing the safety of an experimental drug called felzartamab in 14 people with lupus nephritis, a serious kidney disease caused by lupus. The drug is designed to target specific immune cells that cause harmful inflammation and damage in the kidneys. Researchers will monitor patients for side effects and check if the drug helps reduce protein in the urine and improve kidney function over two years.

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Contacts and locations

Locations

  • Accurate Clinical Research - Katy

    Katy, Texas, 77449, United States

  • CEMIC

    CABA, Buenos Aires F.D., C1431FWO, Argentina

  • Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM)

    Montreal, Quebec, H2X 3J4, Canada

  • ClinCept, LLC/River City Vascular Specialists LLC

    Columbus, Georgia, 31904, United States

  • Clinica Priv Velez Sarsfield

    Córdoba, Córdoba Province, X5016, Argentina

  • Georgia Nephrology - Lawrenceville

    Lawrenceville, Georgia, 30046, United States

  • Hospital Britanico de Buenos Aires

    Caba, Buenos Aires F.D., C1280AEB, Argentina

  • Joseph S. and Diane H. Steinberg Ambulatory Care Center

    Brooklyn, New York, 11201, United States

  • Monash Health

    Melbourne, Victoria, 3168, Australia

  • Precision Comprehensive Clinical Research Solutions - Grapevine

    Grapevine, Texas, 76051, United States

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Prolato Clinical Research Center

    Houston, Texas, 77054, United States

  • R & H Clinical Research

    Katy, Texas, 77450, United States

  • SUNY Downstate Medical Center

    Brooklyn, New York, 11203, United States

  • St. Paul's Hospital

    Vancouver, British Columbia, V6Z1Y6, Canada

  • Stanford University Medical Center

    Stanford, California, 94305, United States

  • The Ohio State University (OSU)

    Columbus, Ohio, 43210, United States

  • University Health Network - Toronto General Division

    Toronto, Ontario, MST258, Canada

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California, San Diego (UCSD)

    La Jolla, California, 92037, United States

  • University of California, San Francisco (UCSF)

    San Francisco, California, 94143, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Western Health

    Saint Albans, Victoria, 3021, Australia

  • Westmead Hospital

    Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.