Poop pills? no, stool transplants aim to cure recurrent c. diff

NCT ID NCT03562741

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether transplanting stool from a healthy donor into the colon can prevent recurrent C. diff infections. The procedure, done via colonoscopy, aims to restore good bacteria that keep C. diff in check. Researchers are tracking 500 people to see if this stops diarrhea from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fecal microbiota transplantation (stool from a healthy donor)

What this could lead to

If successful, this could offer a reliable way to prevent repeat C. diff infections without relying on antibiotics.

What could go wrong

This is an observational study, not a controlled trial, so results may be less conclusive. Risks include infection from donor stool or procedure complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis Clostridium infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • UMass Memorial Medical Center

    RECRUITING

    Worcester, Massachusetts, 01655, United States

    Contact Email: •••••@•••••

    Contact