New trial tests deep sleep vs. strong meds for hidden seizures
NCT ID NCT05263674
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether putting people into a deep sleep with strong sedatives works better than giving more seizure drugs for a serious condition called non-convulsive status epilepticus (NCSE). In NCSE, the brain has ongoing seizure activity without obvious shaking. The trial will include 140 adults who did not get better with standard treatments. Researchers will check if the seizures stop within 24 hours and track any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Propofol (with possible low-dose Midazolam)
What this could lead to
If successful, this could establish a more effective standard treatment for a serious seizure emergency, potentially reducing brain damage and complications.
What could go wrong
This is a Phase 3 trial but still relatively small (140 participants). Deep sedation carries risks like breathing problems or infections, and the results may not apply to all patients.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aarhus Universitetshospital
RECRUITINGAarhus, 8200, Denmark
Contact
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Department of Neurology
RECRUITINGHerlev, 2730, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Odense University Hospital
RECRUITINGOdense, 5000, Denmark
Contact Email: •••••@•••••
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Rigshospitalet
RECRUITINGCopenhagen, 2100, Denmark
Contact
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University Hospital of Zealand
RECRUITINGRoskilde, 4000, Denmark
Contact