Cure My Disease

Don't miss your cure!

 Log in / Sign up

New trial tests deep sleep vs. strong meds for hidden seizures

NCT ID NCT05263674

Recruiting now Disease control Sponsor: University of Southern Denmark Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether putting people into a deep sleep with strong sedatives works better than giving more seizure drugs for a serious condition called non-convulsive status epilepticus (NCSE). In NCSE, the brain has ongoing seizure activity without obvious shaking. The trial will include 140 adults who did not get better with standard treatments. Researchers will check if the seizures stop within 24 hours and track any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Propofol (with possible low-dose Midazolam)
What this could lead to
If successful, this could establish a more effective standard treatment for a serious seizure emergency, potentially reducing brain damage and complications.
What could go wrong
This is a Phase 3 trial but still relatively small (140 participants). Deep sedation carries risks like breathing problems or infections, and the results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON-CONVULSIVE STATUS EPILEPTICUS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Status Epilepticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-CONVULSIVE STATUS EPILEPTICUS

Contacts and locations

Locations

  • Aarhus Universitetshospital

    RECRUITING

    Aarhus, 8200, Denmark

  • Department of Neurology

    RECRUITING

    Herlev, 2730, Denmark

  • Odense University Hospital

    RECRUITING

    Odense, 5000, Denmark

  • Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

  • University Hospital of Zealand

    RECRUITING

    Roskilde, 4000, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.