New nasal spray could tame stage fright in social anxiety
NCT ID NCT06358651
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether a nasal spray called fasedienol can quickly reduce anxiety during a public speaking challenge in adults with social anxiety disorder. About 238 participants will receive either the spray or a placebo before speaking. The study also looks at long-term safety for up to 12 months of use as needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fasedienol nasal spray
- What this could lead to
- If successful, this could offer a fast-acting, on-demand treatment for anxiety triggered by public speaking in people with social anxiety disorder.
- What could go wrong
- This is a Phase 3 trial, but results are not yet known. The effect may be modest, and the spray is only for acute episodes, not a long-term solution. Side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Vistagen Clinical Site
Phoenix, Arizona, 85012, United States
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Vistagen Clinical Site
Fayetteville, Arkansas, 72703, United States
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Vistagen Clinical Site
Little Rock, Arkansas, 72211, United States
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Vistagen Clinical Site
Lafayette, California, 94549, United States
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Vistagen Clinical Site
Oceanside, California, 92056, United States
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Vistagen Clinical Site
Sherman Oaks, California, 91403, United States
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Vistagen Clinical Site
Denver, Colorado, 80209, United States
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Vistagen Clinical Site
Cromwell, Connecticut, 06416, United States
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Vistagen Clinical Site
Jacksonville, Florida, 32256, United States
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Vistagen Clinical Site
Lakeland, Florida, 33803, United States
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Vistagen Clinical Site
Orlando, Florida, 32801, United States
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Vistagen Clinical Site
West Palm Beach, Florida, 33407, United States
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Vistagen Clinical Site
Chicago, Illinois, 60612, United States
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Vistagen Clinical Site
Overland Park, Kansas, 66210, United States
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Vistagen Clinical Site
Baltimore, Maryland, 21208, United States
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Vistagen Clinical Site
Boston, Massachusetts, 02131, United States
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Vistagen Clinical Site
Saint Charles, Missouri, 63304, United States
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Vistagen Clinical Site
Las Vegas, Nevada, 89119, United States
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Vistagen Clinical Site
New York, New York, 10128, United States
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Vistagen Clinical Site
Media, Pennsylvania, 19063, United States
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Vistagen Clinical Site
Memphis, Tennessee, 38119, United States
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Vistagen Clinical Site
Fort Worth, Texas, 76104, United States
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Vistagen Clinical Site
Draper, Utah, 84020, United States
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Vistagen Clinical Site
Everett, Washington, 98201, United States
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