New eye injection trial aims to halt vision loss in severely nearsighted patients

NCT ID NCT06176352

Summary

This Phase 3 clinical trial is testing whether faricimab eye injections can safely control abnormal blood vessel growth that causes vision loss in people with severe nearsightedness. The study will compare faricimab to the standard treatment, ranibizumab, in 280 participants who haven't received previous treatment for this condition. Researchers will measure changes in vision clarity and monitor side effects over time.

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Contacts and locations

Locations

  • A.O. Universitaria S. Maria Della Misericordia Di Udine

    Udine, Veneto, 33100, Italy

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Asia Pacific Eye Centre

    Singapore, 258500, Singapore

  • Beijing Hospital of Ministry of Health

    Beijing, 100730, China

  • Beijing Tong Ren Hospital, Capital Medical University

    Beijing, 100730, China

  • Beijing Tsinghua Changgung Hospital

    Beijing, 102218, China

  • CHU Nantes - Hotel Dieu

    Nantes, 44093, France

  • Central Theater General Hospital of the Chinese People's Liberation Army

    Wuhan, China

  • Centre For Eye Research Australia

    East Melbourne, Victoria, 3002, Australia

  • Centre Paradis Monticelli

    Marseille, 13008, France

  • Centres Ophtalmologique St Exupéry

    Saint-Cyr-sur-Loire, 37540, France

  • Centrum Diagnostyki i Mikrochirurgii Oka LENS

    Olsztyn, 10-424, Poland

  • Centrum Medyczne UNO-MED

    Krakow, 31-070, Poland

  • Chi De Creteil

    Créteil, 94010, France

  • Clinica Universitaria de Navarra

    Pamplona, Navarre, 31008, Spain

  • Complejo Hospitalario Universitario de Santiago.

    Santiago de Compostela, LA Coruna, 15706, Spain

  • Eye & ENT Hospital of Fudan University

    Shanghai, 200030, China

  • Eye Hospital, Wenzhou Medical University

    Wenzhou, 325027, China

  • Far Eastern Memorial Hospital

    New Taipei City, 220, Taiwan

  • First Hospital of China Medical University

    Shenyang, 110001, China

  • Fondation Rothschild

    Paris, 75940, France

  • Fondazione G.B. Bietti Per Lo Studio E La Ricerca in Oftalmologia-Presidio Ospedaliero Britannico

    Rome, Lazio, 00184, Italy

  • Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico-Clinica Regina Elena

    Milan, Lombardy, 20100, Italy

  • Gabinet Okulistyczny Jerzy Mackiewicz

    Lublin, 20-064, Poland

  • Gabinet Okulistyczny Prof Edward Wylegala

    Katowice, 40-594, Poland

  • Hong Kong Eye Hospital

    Mong Kok, Hong Kong

  • Hopital Lariboisiere

    Paris, 75010, France

  • Hopital de la croix rousse

    Lyon, 69317, France

  • Hospital Universitario Puerta de Hierro

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario de Bellvitge

    L'Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Hospital de la Arruzafa. Servicio de Oftalmologia

    Córdoba, 14012, Spain

  • Kim's Eye Hospital

    Seoul, 07301, South Korea

  • Klinika Okulistyczna ?Jasne Blonia? Sp. z o. o.

    ?ód?, 91-134, Poland

  • Knappschaftsklinikum Saar GmbH

    Sulzbach, 66280, Germany

  • National Taiwan University Hospital

    Zhongzheng Dist., 10002, Taiwan

  • National University Hospital

    Singapore, 119074, Singapore

  • OFTALMIKA Sp. z o.o

    Bydgoszcz, 85-631, Poland

  • Oftalvist

    Madrid, 28006, Spain

  • Ospedale Clinicizzato SS Annunziata

    Chieti, Abruzzo, 66100, Italy

  • Ospedale Monaldi - AORN dei Colli

    Naples, Campania, 80131, Italy

  • Peking Union Medical College Hospital

    Beijing, 100730, China

  • Policlinico di Bari

    Bari, Apulia, 70124, Italy

  • Qingdao Eye Hospital of Shandong First Medical University

    Qingdao, 265299, China

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, 03722, South Korea

  • Shanghai First People's Hospital

    Shanghai, 200080, China

  • Shanxi Eye Hospital

    Taiyuan, 030002, China

  • Singapore Eye Research Institute

    Singapore, 168751, Singapore

  • Strathfield Retina Clinic

    Strathfield, New South Wales, 2135, Australia

  • Sydney Eye Hospital

    Sydney, New South Wales, 2000, Australia

  • Sydney Retina Clinic and Day Surgery

    Sydney, New South Wales, 2000, Australia

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Tan Tock Seng Hospital

    Singapore, 308433, Singapore

  • The 2nd Affiliated Hospital of Harbin Medical University

    Harbin, 150001, China

  • The Second Hospital of Jilin University

    Changchun, 130041, China

  • The University of Hong Kong

    Hong Kong, Hong Kong

  • Universitatsklinikum Koln

    Cologne, 50937, Germany

  • Universitätsklinikum Freiburg, Klinik für Augenheilkunde

    Freiburg im Breisgau, 79106, Germany

  • Wuxi No.2 People's Hospital

    Wuxi, 214000, China

  • Xi'an People's Hospital (Xi'an Fourth Hospital)

    Xi'an, China

  • Yeungnam University Medical Center

    Daegu, 42415, South Korea

  • Zhongshan Ophthalmic Center, Sun Yat-sen University

    Guangzhou, 510060, China

Conditions

Explore the condition pages connected to this study.