Smart scan may personalize esophageal cancer therapy

NCT ID NCT07385664

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests whether a special PET scan (FAPI-PET/CT) can help doctors choose the best treatment for people with resectable esophageal cancer. After two cycles of chemoimmunotherapy, the scan results will guide whether patients continue with more chemoimmunotherapy or switch to chemoradiation. The study aims to improve the chance of a complete response (no cancer left after treatment) and involves 66 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

chemoimmunotherapy and concurrent chemoradiotherapy

What this could lead to

If successful, this could lead to a more personalized treatment approach for esophageal cancer, potentially improving response rates and reducing unnecessary side effects.

What could go wrong

This is an early phase II trial with only 66 participants, so results may not apply to everyone. The approach is complex and may not improve outcomes over standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

esophageal cancer esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••