New MRI scan could help surgeons avoid facial nerve damage during brain tumor removal

NCT ID NCT04057976

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study tested a special MRI technique called diffusion tensor tractography (DTT) to map the facial nerve before surgery for vestibular schwannoma, a benign brain tumor. The facial nerve is at risk during surgery, and injury can cause permanent facial weakness. The study involved 38 adults scheduled for surgery, who received an extra 10-minute MRI scan. Researchers compared the nerve position seen on the MRI with what surgeons found during the operation to see how accurate the technique was.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
probabilistic diffusion tensor tractography (DTT) MRI sequence
What this could lead to
If successful, this MRI technique could help surgeons see the facial nerve before operating, potentially reducing the chance of permanent facial weakness.
What could go wrong
This is a small, completed study with only 38 participants. The technique may not be reliable enough for routine use, and results need confirmation in larger trials.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • King's College Hospital NHS Foundation Trust

    London, London, SE5 9RS, United Kingdom

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