New eye injection aims to halt blinding disease in seniors

NCT ID NCT05811351

Completed Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This study tested whether an experimental injection into the eye (called JNJ-81201887) could slow the progression of geographic atrophy, a late-stage form of age-related macular degeneration that causes permanent vision loss. It involved 305 participants who received either the real injection or a sham (pretend) procedure. The main goal was to see if the treatment could reduce the growth rate of the damaging eye lesions over 18 months.

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Contacts and locations

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Locations

AXON Clinical s.r.o.

Prague, 15000, Czechia
Aalborg University Hospital

Aalborg, 9000, Denmark
Adelaide Eye and Retina Centre

Adelaide, 5000, Australia
Alberta Retina Consultants

Edmonton, Alberta, T5H 0X5, Canada
Amsterdam University Medical Centers Location Academic Medical Center

Amsterdam, 1105 AZ, Netherlands
Ankara Bilkent Sehir Hastanesi

Ankara, 06800, Turkey (Türkiye)
Arcispedale S. Anna Ferrara

Ferrara, 44124, Italy
Asheville Eye Associates - Western Carolina Retinal Associates

Asheville, North Carolina, 28803, United States
Associated Retinal Consultants P.C.

Royal Oak, Michigan, 48073, United States
Augenzentrum am St Franziskus Hospital Munster

Münster, 48145, Germany
Austin Clinical Research

Austin, Texas, 78750, United States
Azienda Ospedaliera Univ.- Università Degli studi della Campania - Luigi Vanvitelli

Naples, 80138, Italy
Baskent University Ankara Hospital

Ankara, 06490, Turkey (Türkiye)
Bay Area Retina Associates

Walnut Creek, California, 94598, United States
Bristol Eye Hospital

Bristol, BS1 2LX, United Kingdom
Calgary Retina Consultants

Calgary, Alberta, T2H 0C8, Canada
California Eye Medical Specialists

Pasadena, California, 91107, United States
California Retina Consultants

Oxnard, California, 93036, United States
Cascade Medical Research Institute, LLC

Springfield, Oregon, 97477, United States
Casey Eye Institute

Portland, Oregon, 97239, United States
Central Middlesex Hospital

London, NW10 7NS, United Kingdom
Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman

Liège, 4000, Belgium
Centre for Eye Research Australia

East Melbourne, 3002, Australia
Centro Medico Teknon S.L.

Barcelona, 08022, Spain
Centro de Oftalmologia Barraquer

Barcelona, 08021, Spain
Charite Universitaetsmedizin Berlin

Berlin, 12203, Germany
Charles Retina Institute

Germantown, Tennessee, 38138, United States
Charleston Neuroscience Institute, LLC

Beaufort, South Carolina, 29902, United States
Cincinnati Eye Institute

Cincinnati, Ohio, 45242, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Clinica Baviera Madrid Castellana

Madrid, 28046, Spain
Clinica Oftalvist Valencia

Burjassot, 46100, Spain
Clinica Univ. de Navarra

Pamplona, 31008, Spain
Colorado Retina - Lakewood Clinic

Lakewood, Colorado, 80228, United States
Cumberland Valley Retina Consultants

Hagerstown, Maryland, 21740, United States
Dokuz Eylul University Hospital

Izmir, 35330, Turkey (Türkiye)
Duke University

Durham, North Carolina, 27705-4699, United States
East Florida Eye Institute

Stuart, Florida, 34994, United States
Erie Retina Research

Erie, Pennsylvania, 16505, United States
Espaco Medico de Coimbra

Coimbra, 3030-163, Portugal
Eszak Pesti Centrumkorhaz Honvedkorhaz

Budapest, 1062, Hungary
Fakultni nemocnice Kralovske Vinohrady

Prague, 100 34, Czechia
Fondazione IRCCS Ca Granda Ospedale Policlinico Di Milano

Milan, 20122, Italy
Fort Lauderdale Eye Institute

Plantation, Florida, 33324, United States
Foundation for Vision Research

Grand Rapids, Michigan, 49546, United States
Ganglion Orvosi Központ

Pécs, 7621, Hungary
Georgia Retina

Marietta, Georgia, 30060, United States
Graystone Eye

Hickory, North Carolina, 28602, United States
Hacettepe University Hospital

Ankara, 06230, Turkey (Türkiye)
Het Oogziekenhuis Rotterdam

Rotterdam, 3011, Netherlands
Hosp Univ Fund Jimenez Diaz

Madrid, 28040, Spain
Hosp. Clinico Univ. Lozano Blesa

Zaragoza, 50009, Spain
Hosp. Dos de Maig

Barcelona, 08025, Spain
Hosp. La Arruzafa

Córdoba, 14012, Spain
Hosp. Prov. Do Conxo

Santiago de Compostela, 15706, Spain
Hosp. Univ. 12 de Octubre

Madrid, 28041, Spain
Hosp. Univ. Donostia

Donostia / San Sebastian, 20014, Spain
Hosp. Univ. Miguel Servet

Zaragoza, 50009, Spain
Hosp. Univ. Pta. de Hierro Majadahonda

Majadahonda, 28222, Spain
Hosp. Virgen Del Rocio

Seville, 41013, Spain
Houston Eye Associates

Houston, Texas, 77025, United States
Idc Salud Hosp. Gral. de Catalunya

Sant Cugat del Vallès, 08195, Spain
Inselspital Universitatsspital Bern

Bern, 3010, Switzerland
Inst. Cat. de Retina

Barcelona, 08022, Spain
Inst. de Microcirugia Ocular

Barcelona, 08035, Spain
Institut De L'oeil Des Laurentides

Boisbriand, Quebec, J7H 0E8, Canada
Jules Stein Eye Institute UCLA

Los Angeles, California, 90095, United States
Klinikum Gottingen der Georg August Universitat

Göttingen, 37075, Germany
Klinikum Ludwigshafen

Ludwigshafen am Rhein, 67063, Germany
Konya Selcuk University Medical Faculty

Konya, 42250, Turkey (Türkiye)
Long Island Vitreo Retinal Consultants

Great Neck, New York, 11021, United States
Maine Eye Center

Portland, Maine, 04101, United States
Manchester Royal Eye Hospital

Manchester, M13 9WL, United Kingdom
Marietta Eye Clinic

Marietta, Georgia, 30060, United States
MedEye Associates

Miami, Florida, 33143, United States
Medizinische Hochschule Hannover

Hanover, 30625, Germany
Midwest Eye Institute

Carmel, Indiana, 46032, United States
Moorfields Eye Hospital

London, EC1V 2PD, United Kingdom
NC Retina Associates

Wake Forest, North Carolina, 27587, United States
National Opthalmic Research Institute

Fort Myers, Florida, 33912, United States
OFTEX Ltd. - EYE CENTER

Pardubice, 530 02, Czechia
Oculomedica

Bydgoszcz, 85 157, Poland
Oftalmika

Bydgoszcz, 85 631, Poland
Ophthalmic Consultants of Boston

Boston, Massachusetts, 02114, United States
Opthalmic Consultants of the Capital Region

Troy, New York, 12180, United States
Ospedale San Raffaele

Milan, 20132, Italy
Oxford Eye Hospital

Oxford, OX3 9DU, United Kingdom
Panhandle Eye Group LLP-Southwest Retina Specialists

Amarillo, Texas, 79106, United States
Piedmont Eye Center

Lynchburg, Virginia, 24502, United States
Policlinico Universitario Agostino Gemelli

Roma, 00168, Italy
Radboudumc

Nijmegen, 6525 GA, Netherlands
Retina Associates

Elmhurst, Illinois, 60126, United States
Retina Associates Of South Texas P A

San Antonio, Texas, 78240, United States
Retina Associates Of Southern California

Huntington Beach, California, 92647, United States
Retina Associates Southwest PC

Tucson, Arizona, 85704, United States
Retina Associates of Utah P C

Salt Lake City, Utah, 84107, United States
Retina Consultants PLLC

Slingerlands, New York, 12159, United States
Retina Consultants San Diego

Poway, California, 92064, United States
Retina Consultants of Minnesota

Saint Louis Park, Minnesota, 55416, United States
Retina Consultants of Orange County

Fullerton, California, 92835, United States
Retina Consultants of Southern California

Redlands, California, 92374, United States
Retina Consultants of Texas

San Antonio, Texas, 78240, United States
Retina Consultants of Texas

The Woodlands, Texas, 77384, United States
Retina Consultants of Texas 2

Bellaire, Texas, 77401, United States
Retina Foundation of the Southwest

Dallas, Texas, 75231, United States
Retina Group of Florida

Fort Lauderdale, Florida, 33308, United States
Retina Research Institute of Texas

Abilene, Texas, 79606, United States
Retina Specialists

Baltimore, Maryland, 21204, United States
Retina Specialty Institute

Pensacola, Florida, 32503, United States
Retina Vitreous Associates of Florida

St. Petersburg, Florida, 33711, United States
Retina and Vitreous of Texas, PLLC

Bellaire, Texas, 77401, United States
Retina-Vitreous Surgeons of Central New York

Liverpool, New York, 13088, United States
Retinal Research Institute

Phoenix, Arizona, 85053, United States
Rocky Mountain Retina Consultants

Salt Lake City, Utah, 84107, United States
Royal Victoria Infirmary

Newcastle upon Tyne, NE1 4LP, United Kingdom
S:t Eriks Ogonsjukhus

Stockholm, 171 64, Sweden
Sacco Hospital

Milan, 20157, Italy
San Antonio Eye Center

San Antonio, Texas, 78215, United States
Shiley Eye Institute Jacobs Retina Center

La Jolla, California, 92093 0946, United States
Sierra Eye Associates

Reno, Nevada, 89502, United States
Southampton University Hospital

Southampton, SO16 6YD, United Kingdom
Spokane Eye Clinical Research

Spokane, Washington, 99204, United States
Stanford Health Care

Palo Alto, California, 94303, United States
Strategic Clinical Research Group

Willow Park, Texas, 76087, United States
Strathfield Retina Clinic

Strathfield, 2135, Australia
Sydney Retina Clinic and Day Surgery

Sydney, 2000, Australia
Sydney West Retina

Westmead, 2145, Australia
Texas Retina Associates

Dallas, Texas, 75231, United States
Texas Retina Associates 1

Fort Worth, Texas, 76104, United States
The Ottawa Hospital Research Institute

Ottawa, Ontario, K1H 8L6, Canada
The Retina Care Center

Baltimore, Maryland, 21209, United States
The Retina Centre of Ottawa

Ottawa, Ontario, K2B 7E9, Canada
The Retina Clinic London

London, W1G 9AX, United Kingdom
The Retina Group of Washington

Chevy Chase, Maryland, 20815, United States
The Retina Institute

St Louis, Missouri, 63144, United States
The Retina Partners

Los Angeles, California, 91436, United States
UT Southwestern

Dallas, Texas, 75390, United States
UZ Gent

Ghent, 9000, Belgium
UZ Leuven Gasthuisberg

Leuven, 3000, Belgium
Uls Coimbra - Hosp. Univ. Coimbra

Coimbra, 3000 075, Portugal
Uls Sao Joao - Hosp. Sao Joao

Porto, 4200 319, Portugal
Universitaets-Augenklinik Bonn

Bonn, 53127, Germany
Universitaetsklinikum Leipzig

Leipzig, 04103, Germany
Universitaetsklinikum Muenster

Münster, 48149, Germany
Universitaetsklinikum Tuebingen

Tübingen, 72076, Germany
Universitatsklinikum Gießen - Klinik und Poliklinik fur Augenheilkunde

Giessen, 35392, Germany
Universitatsklinikum Schleswig Holstein Kiel

Kiel, 24105, Germany
University Hospital Of Copenhagen, Glostrup Hospital

Glostrup Municipality, 2600, Denmark
University Of Illinois

Chicago, Illinois, 60612, United States
University Retina

Lemont, Illinois, 60439, United States
University of Utah

Salt Lake City, Utah, 84132, United States
Uno Med

Tarnów, 33 100, Poland
Verum Research LLC

Eugene, Oregon, 97401, United States
Vitreo Retinal Associates-Worcester

Worcester, Massachusetts, 01605, United States
VitreoRetinal Associates, PA

Gainesville, Florida, 32607, United States
Vitreous Retina Macula Consultants of New York

New York, New York, 10022, United States
Wagner Kapoor Research institute

Norfolk, Virginia, 23502, United States
Warszawski Szpital Okulistyczny

Warsaw, 01 258, Poland
Wills Eye/Mid Atlantic Retina

Cherry Hill, New Jersey, 08034, United States
Zala Megyei Szent Rafael Korhaz

Zalaegerszeg, 8900, Hungary
Zealand University Hospital

Roskilde, 4000, Denmark
Ziekenhuis Oost-Limburg

Genk, 3600, Belgium

Conditions

Explore the condition pages connected to this study.

GEOGRAPHIC ATROPHY