Last-Resort treatment offered for stubborn joint infections

NCT ID NCT06383611

First seen Apr 16, 2026 · Last updated Apr 27, 2026 · Updated 3 times

Summary

This program offers the VT-X7 system to people with serious infections in their hip or knee replacements who have run out of other options. The treatment uses a special irrigation method with two antibiotics (vancomycin and tobramycin) over 7 days during joint replacement surgery. It is for adults aged 22 to 84 who need their old joint replaced due to infection and have already failed a prior replacement attempt.

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Contacts and locations

Locations

  • Banner - University Medical Center Phoenix

    Phoenix, Arizona, 85006, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Dartmouth Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Houston Methodist Medical Center

    Houston, Texas, 77030, United States

  • Integris Southwest Medical Center

    Oklahoma City, Oklahoma, 73109, United States

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Ohio State University

    Columbus, Ohio, 43202, United States

  • Parkview Hospital Orthopedics

    Fort Wayne, Indiana, 46845, United States

  • St. Mary's Regional Hospital - Intermountain Health

    Grand Junction, Colorado, 81501, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45267-0212, United States

  • University of Florida Health

    Gainesville, Florida, 32608, United States

  • University of Iowa

    North Liberty, Iowa, 52317, United States

  • University of Missouri Health Care

    Columbia, Missouri, 65212, United States

Conditions

Explore the condition pages connected to this study.