Last-Resort leukemia drug made available to 29 patients

NCT ID NCT07517315

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This program provides continued access to the drug vodobatinib for people with Philadelphia chromosome-positive chronic myeloid leukemia (CML) whose cancer has not responded to prior treatments. After the main study was stopped early for non-safety reasons, 29 patients who were still benefiting from the drug were allowed to keep receiving it. Their care is managed by their own doctors according to local standards.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vodobatinib

What this could lead to

If successful, this could provide a treatment option for people with chronic myeloid leukemia who have not responded to other therapies.

What could go wrong

This is an expanded access program, not a formal trial, so results are limited. The main study was stopped early, and only 29 patients are included.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Colentina Clinical Hospital

    Bucharest, Romania

  • Georgia Cancer Center at Augusta University

    Augusta, Georgia, 30912, United States

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

  • IRCCS Romagnolo Institute for the Study of Tumors "Dino Amadori"

    Meldola, FC, 47014, Italy

  • Léon Bérard Center

    Lyon, 69373, France

  • Meenakshi Mission Hospital and Research Centre

    Madurai, India

  • Oncology Institute "Prof. Dr. Ion Chiricuță"

    Cluj-Napoca, Romania

  • Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer

    Navi Mumbai, India

  • University of Debrecen, Clinical Center Institute of Internal Medicine

    Debrecen, 4032, Hungary

  • University of Utah Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States