Last-Resort drug access for leukemia patients
NCT ID NCT05918913
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This program provides revumenib (SNDX-5613) to patients with relapsed or refractory acute leukemias who cannot join other studies and have no approved treatments. Participants take the drug orally every 12 hours. The goal is to offer a potential treatment option in a controlled setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Revumenib (also called SNDX-5613)
- What this could lead to
- If it works, this could offer a treatment option for people with hard-to-treat acute leukemias who have run out of standard therapies.
- What could go wrong
- This is an expanded access program, not a formal trial, so results are not systematically collected. The drug is still investigational and may not work for everyone; side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Advent Health Orlando
Orlando, Florida, 32804, United States
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Alabama Center for Childhood Cancer And Blood Disorders, Children's of Alabama
Birmingham, Alabama, 35233, United States
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Center for Cancer and Blood Disorders, Colorado Children's Hospital
Aurora, Colorado, 80045, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital
New Orleans, Louisiana, 70118, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Mercy Hospital-Kansas City
Kansas City, Missouri, 64108, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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City of Hope
Duarte, California, 91010, United States
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City of Hope at Orange County Lennar Foundation Cancer Center
Irvine, California, 92618, United States
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Dana-Farber Cancer Institute, Boston Children's Cancer and Blood Disorders Center
Boston, Massachusetts, 02215, United States
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Division of Hematology and Hematologic Malignancies, University of Utah-Huntsman Cancer Hospital
Salt Lake City, Utah, 84112, United States
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Division of Hematology and Oncology, Division of Pulmonary, Critical Care and Sleep Medicine, Vontz Center for Molecular Studies
Cincinnati, Ohio, 45267, United States
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Doernbecher Children's Hospital, Oregon Health & Science University
Portland, Oregon, 97239, United States
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Duke University Medical Center
Durham, North Carolina, 27705, United States
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HCTU, Division of Hematology, University of Colorado, Anschutz Medical Center
Aurora, Colorado, 80045, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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Lucile Packard Children's Hospital-Stanford
Palo Alto, California, 94304, United States
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Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Memorial Hermann-Texas Medical Center
Houston, Texas, 77030, United States
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Memorial Sloan Kettering Cancer Center
Long Island City, New York, 10065, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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OSU Medical Center
Columbus, Ohio, 43210, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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Rady Children's Hospital
San Diego, California, 92123, United States
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Seattle Children's Research Institute, Seattle Childrens Hospital
Seattle, Washington, 98105, United States
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Siteman Cancer Center - Washington University
St Louis, Missouri, 63110, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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UCLA, UCLA RRMC, Drug Information Center, Department of Pharmaceutical Services Drug Supply Shipment
Los Angeles, California, 90095, United States
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University of California, San Francisco
San Francisco, California, 94158, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
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Winship Cancer Institute at Emory University
Atlanta, Georgia, 30322, United States